like fungi and bacterias which is naturally produced Phytoalexin is called as resveratrol.Chemical synthesis also been used to produce this resveratrol. It is sold by the Nutritional supplement which is derived form the Japanese knot weed.This experienced in rats and mouse which results in blood – sugar lowering,anti-inflammatory,anti-cancer and some other cardiovascular effects have been resulted finally.In humans also some of this symptoms are replicated. Trial of this heavy dose (3-5g) of resveratrol on human results in lower blood sugar.This resveratrol is found in red wine and on the skin of the red grapes.This experiment shows that resveratrol treatment can extends the life of the short-lived fish, fruits flies and nematode worms but is is unable to extend the life of mice.In 2003 Howitz and Sinclair groups reported that resveratrol treatment can increase the life span of yeast Saccharomyces cerevisiae.Later Sinclair studies conducted that this experiment can give life span to the Drosophila melanogaster which is the fruit flies and worm Caenorhabditis elegans.

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